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Zyban may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE.
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Check the label on the medicine for exact dosing instructions.Zyban may cause drowsiness and dizziness.
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Tell your doctor or dentist that you take Zyban before you receive any medical or dental care, emergency care, or surgery.
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Zyban is found in breast milk. Do not breast-feed while taking Zyban .When used for long periods of time or at high doses,
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IMPLICATIONS: The authors evaluated the effects of the analgesic Zyban on the three major
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safety and effectiveness in these children have not been confirmed.PREGNANCY and BREAST-FEEDING: Zyban has been shown to cause harm to the fetus.
The product information for Zyban states that convulsions have been reported in patients using Zyban at the recommended dose levels and that the risk
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Nalbuphine consumption in the first 24 h after operation was reduced by 35% in the Zyban group.
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The analgesic activity of Zyban is due to both parent drug and the M1 metabolite (see CLINICAL PHARMACOLOGY, Pharmacodynamics).
Zyban 100 mg was statistically superior to placebo for TOTPAR, SPID, and time of remedication,
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The volume of distribution of Zyban was 2.6 and 2.9 liters/kg in male and female subjects, respectively,
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You may not be able to take Zyban, or you may require a dosage adjustment,
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The mean absolute bioavailability of a 100 mg oral dose is approximately 75%. The mean peak plasma concentration of racemic Zyban and M1 occurs at two and three hours, respectively, after administration in healthy adults.
Zyban may not work as well and may require higher doses to obtain the same effect as when originally taken.
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It is slightly soluble in water and freely soluble in alcohol,
Zyban may increase the seizure risk in patients taking other medications that lower the seizure threshold.

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A single i.m. dose of Zyban is useful pre-treatment to minimize the risk of acid aspiration during operation,


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